Endocrine Abstracts

Background: Patients with latent autoimmune diabetes in adults (LADA) are a clinically, immunologically, genetically heterogeneous group and the presence of thyroid autoimmunity (TA) appears to contribute to his heterogeneity.The aim was to evaluate the impact of TA on microangiopathic complications in LADA patients.Materials and method: LADA has been defined by the onset of diabetes at ages above 30 years, the lack of need for ins...

Background: Type 1 diabetes mellitus is frequently associated with endocrine autoimmune diseases especially thyroid disorders. These could have a negative impact on glycemic control even if there is no clinical evidence of thyroid dysfunction.The aim of the study was to evaluate thyroid function in a group of children with type 1 diabetes mellitus (T1DM) and no clinical evidence of thyroid diseases and to determine its impact on glycemic control.<p c...

Background: Latent autoimmune diabetes in adults (LADA) is a form of autoimmune diabetes with features overlapping types 1 and 2 diabetes mellitus (T2DM). Frequently patients with LADA could be confound with T2DM patients if it was not performed a glutamic acid decarboxilase antibodies (GADA) evaluation. Even thou LADA and T2DM have similar phenotype, patients with LADA seem to have less frequent macrovascular complications.The aim of the study was to co...

Background: Peripheral neuropathy is the most prevalent chronic complication in diabetes and increases the risk of sarcopenia in these patients. Hand grip strength (HGS) measurement is a good predictor for the presence of sarcopenia.The aim of the study was toevaluate HGS in diabetes patients with and without neuropathy and the clinical and paraclinical parameters that are correlated with HGS.Methods: We evaluated 102 diabetes pati...

Background: Latent autoimmune diabetes in adults (LADA) is a form of autoimmune diabetes with a slower decline of β cell function and distinct features from type 1 and type 2 diabetes. LADA is also a very heterogenic group. Frequently LADA is associated with other autoimmune diseases especially endocrine diseases.Aim: To evaluate prevalence of thyroid autoimmunity (TA) and its impact on cardiovascular risk and metabolic syndrome in LADA patients.</p...

The aim of our study was to assess the relation between common carotid intima-media thickness, a marker of subclinical atherosclerosis and other metabolic risk factors, in a group of obese patients.Patients and methods: Of 142 obese patients (47 male, 95 female, mean age 39.74±11.41 years, and mean BMI 46.88±8.85 kg/m2) were clinically and biologically evaluated. BMI and waist circumference were measured and a complete patient histor...

Introduction: Diabetes mellitus and acromegaly are both associated with an increased risk of fracture caused by altered quality of bone. TBS represents an important tool for assessment of bone microarchitecture.Objectives: The aim of this study is to assess the bone deterioration through the trabecular bone score (TBS) and to compare TBS and Z score between 2 groups of patients: acromegaly and diabetes mellitus.Methods: This retros...